Research

This Department of Pathology and Laboratory Medicine hosts nationally and internationally recognized research programs covering diverse themes.  Major focused strengths and scientific synergies have emerged within the Department in recent years.

• Department-wide research strengths include neurodegenerative diseases, immunobiology, cancer biology and therapeutics, cardiovascular pathobiology, and HIV immunology
• Research initiatives encompass:
  • intracellular signaling
  • molecular mechanisms of leukemogenesis and sarcomagenesis, with special emphasis on aberrant transcriptional factors; RNA pathobiology
  • cellular development, such as lymphocyte, melanocyte, and bone development
  • endothelial cell and platelet pathobiology
  • metastasis and behavior of cells in situ and in three-dimensions
  • proteomics and protein modeling
  • emerging infectious diseases, including HIV
  • neurodegenerative mechanisms
  • experimental therapeutics
• Inter-disciplinary programs support translational research efforts and clinical trials, leveraging the expertise of departmental faculty members with clinical service missions, and promote development of new clinical diagnostic tests
• Department-based institutes and centers, such as the Institute for Medicine and Engineering and the Institute on Aging, strengthen interdisciplinary research
  
• National prominence in the field of immunology derives from hosting prestigious forums, including the AAI Introductory Courses in Immunology and the US/Japan Cooperative Medical Science Program.
• Resource laboratories founded by the Department offer access to cutting-edge molecular, imaging and bioinformatics technologies