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Medical School Electives
The Department currently offers these electives:
PAT302 - Autopsy Pathology at Hospital of the University of Pennsylvania (HUP)
Description: Students will function as pathology residents working with members of the pathology staff at HUP to learn and perform autopsy procedures. The primary concern will be the careful study of selected cases which illustrate important pathological processes and clinical correlations.
Director: Dr. Carolyn Cambor
7.021 Founders Bldg.
3400 Spruce Street
Philadelphia, PA 19104
Tel. (215) 615-1428
Carolyn.Cambor@uphs.upenn.edu
PAT304D - Autopsy & Surgical Pathology at Pennsylvania Hospital
Description: Offers experience in a laboratory which examines a large volume of interesting cases using state-of-the-art technology, including immunohistochemistry, in-situ-hybridization, electron microscopy, flow cytometry, and image analysis. Students participate in gross dissection and microscopic examination of surgical specimens and assist in autopsies. Students participate with the pathology residents in all departmental teaching conferences. An extensive departmental library and collection of teaching slides are available for student use during the rotation.
Director: Dr. Helen Haupt
Pennsylvania Hospital
8th and Spruce Streets
Philadelphia, PA 19107
Tel.(215) 829-3544
haupth@pahosp.com
PAT300 - Surgical Pathology at HUP
Description: The student describes and dissects surgically removed tissues and organs and, under supervision, prepares the material for microscopic examination and diagnosis. The clinical, anatomical, and molecular information is integrated by appropriate literature review and discussion with the staff.
Director: Antonia Sepulveda, MD, PhD
Hospital of the University of Pennsylvania
3400 Spruce Street
6th Floor Founders Building, Room 6080
Philadelphia, PA 19104
Tel: 215-615-4361
asepu@mail.med.upenn.edu
PAT301 - Clinical Pathology at HUP
Description: The course consists of theoretical and practical applications of specific areas in Laboratory Medicine. The student will rotate through two chosen laboratory areas after meeting with the course director. The disciplines that are available include Transfusion Medicine, Coagulation, Hematology, Immunology, Microbiology, or Clinical Chemistry. Students will become familiar with the theory, performance and appropriate clinical utilization and interpretation of laboratory conferences and consultation rounds. Much instruction also occurs through individual interaction with resident, fellow, faculty and laboratory users. Student responsibilities include written consultation on selected assigned cases –e.g., complex serology or requests for special blood products, and presentation of relevant lab tests during laboratory rounds.
Director: Dr. Eleanor Pollak
316C Abramson CHOP
Philadelphia, PA 19104
Tel. (215) 590-3437
pollak@mail.med.upenn.edu
PAT305 - Pediatric Pathology at Children’s Hospital of Philadelphia (CHOP)
Description: The course seeks to acquaint the medical student with the importance and relevance of surgical and autopsy pathology in the management of patients, especially given the restricted exposure to pathology in current medical school curricula. Integration of clinical information of pathological findings would also be an important objective, essentially experiential. The student will participate in all major daily activities with the department, including autopsies and surgical specimens. Participation at intradepartmental interesting case conferences (3 times a week), as well as assistance at all other interdepartmental and major hospital extradepartmental conferences (brain cutting, GI pathology, pediatric grand rounds, cardiac pathology rounds, etc.), would be expected. During the rotation, the student will be closely supervised by the pathology staff and/or the pathology assistant, and will not be expected to assume sole responsibility for any autopsy or surgical specimen.
Director:Dr. Pierre A. Russo
CHOP
Tel.(215) 590-1739
ruso@email.chop.edu
PAT323 - Immunohematology (Transfusion Medicine) at HUP
Description: The Division of Transfusion Medicine offers a four-week elective for 2nd, 3rd, or 4th year medical students. The course will consist of theoretical and practical applications of blood banking and transfusion medicine. There will be formal lectures as well as informal conferences. Students will learn about the immunologic basis for pre-transfusion testing, management of patients who require blood products, indications for blood products, and workup of suspected transfusion reactions. In addition, students will rotate through a state-of-the-art Apheresis, Infusion, and Blood Donation Center. Here, they will learn the principles and clinical management of patients in need of plasmapheresis, cyapheresis, hematopoietic stemcell collection for transplant, and infusions of recombinant antibodies, enzymes, immune globulins, and other medications.
Director: Dr. Donald Siegel
509 Stellar Chance Lab
422 Curie Blvd.
Philadelphia, PA 19104
Tel. (215) 898-9655
siegeld@mail.med.upenn.edu
PAT334 - Gastrointestinal and Hepatobiliary Pathology
Description: The goals of this course are to introduce the student to the field of academic anatomic pathology and further their understanding of and refine their approach to a variety of disease processes. The student will become an active member of theGI/liver/pancreas pathology team. As such, they will be directly involved and responsible for handling cases for evaluation and sign out. The student will work directly with the GI Fellow and the Director Dr. Emma Furth. They will attend and possibly present at numerous clinical and research conferences. Development of critical thinking and reading of the literature is expected and carried out in part by participation in weekly journal club presentations.
Director: Dr. Emma E. Furth
Tel. 215-662-6503
eef@mail.med.upenn.edu
The Department also offers two, 2-week Frontiers in Medicine Electives called:
Frontiers 505 - Effective Use of Clinical Laboratory Testing
Description: This 2-week course will be taught by over 45 dedicated faculty instructors, house officers, and technologists from the Divisions of Transfusion Medicine and Laboratory Medicine in the Department of Pathology and Laboratory Medicine. The “workshop-type” course is structured to comprise a mix of short lectures, hands-on laboratory demonstrations, and case studies all designed to enhance the students’ ability to use diagnostic tests appropriately. In addition to understanding the medical indications and proper interpretation of the various tests, issues relating to cost-effectiveness and their impact on health care costs will be discussed. Topics to be addressed include: Blood components and transfusion, diagnosis of bleeding disorders, diagnosis of common hematologic (RBC/WBC) disorders, diagnosis of hypercholesterolemia/lipidemia, principles of urinalysis, laboratory assessment of thyroid function, laboratory diagnosis of AIDS, detection of drugs of abuse, therapeutic drug monitoring, laboratory diagnosis of autoimmune disease, interpretation of laboratory tests in clinical microbiology, clinical applications of flow Cytometry, and the use of molecular pathology tests in clinical medicine.
In discussing these various topics, basic science principles, physiology, biochemistry, immunology, etc., is reviewed as they relate to the diagnosis of disease. For example, in the workup of hyperlipidemia, an understanding of what is measured and why naturally leads to a review of lipid metabolism; a discussion of why stored banked platelets “outdate” more quickly than RBCs (because they must be kept at room temperature) leads to a discussion of how platelet microtubules depolymerize to monomeric tubulin in the cold; a discussion of what is measured and why in the diagnosis of HIV infection naturally leads to review of virion, target cell receptors, and immune response, etc.
To understand how many of these measurements/tests are performed, the basics of a number of state-of-the-art technologies are presented, e.g. PCR, Flow Cytometry, microchip technology, etc.
Director: Dr. Donald Siegel
509 Stellar Chance Lab
422 Curie Blvd.
Philadelphia, PA 19104
Tel. 215-898-9655
siegeld@mail.med.upenn.edu
Co-Director: Dr. Eleanor Pollak
316C Abramson CHOP
Philadelphia, PA 19104
Tel.(215) 590-3437
pollak@mail.med.upenn.edu
Frontiers 520 - Aging
Description: This course will explore new advances in an understanding of the basic biology and pathophysiology of aging, including reviews of current genetic and metabolic theories of the causes of aging. It will also review current and experimental therapeutic efforts to slow or reverse deleterious aspects of aging. Further, key psychosocial and clinical issues related to human aging will be discussed from the view of human development across the lifespan.
The course will be divided into 3 general areas:
- Overview of the basic biology of aging
- Physiology of human aging
- Psychosocial aspects of Geriatric Medicine
The course will bring basic science and clinical faculty together in a joint effort that aims to expand awareness of how aging affects human physiology and behavior, and how an understanding of these issues can improve patient care and well-being. Mornings will be reserved for didactic sessions by faculty. Afternoons will be reserved for discussion of journal articles and independent research on an age-related topic in preparation for a required presentation to be given at the end of the week.
Student evaluation will be based on attendance, participation and final presentation.
Director: Dr. Frederick Johnson
450A Stellar Chance
422 Curie Blvd.
Philadelphia, PA 19014
Tel.215-573-5037
johnsonb@mail.med.upenn.edu
Finally, the Department arranges clinical/bench research experience through three mechanisms:
- As part of the post-sophomore “year out” program (Student Pathology Fellowship)
- Individual research elective with a Departmental faculty member
- Individual project involvement with a Departmental faculty member for “Scholarly Pursuit”.
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