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Pediatric Pathology

Overview:

Though administratively separate from the University of Pennsylvania, all this division’s pathology faculty have Penn appointments. This has resulted in maximal integration of its Pathology department with Penn, functioning essentially as the pediatric arm of HUP. While this is an atypical model, its many common initiatives include performing all neonatal autopsies for HUP, running joint fellowship programs, and providing both a complementary educational component and complementary research cores to those at Penn. In the process, it has become the largest pediatric pathology department in the nation.

Simply put, this Division at Children’s Hospital was established in order to:
  • create a stronger affiliation between the Pathology and Laboratory Medicine (P&LM) operations of HUP and CHOP
  • promote CHOP P&LM’s major faculty expansion plans
  • provide outstanding customer-oriented service and patient care
  • become a worldwide academic leader in Pediatric P&LM.

Highlights:

  • Approximately 30 faculty members organized within three “sub-divisions”: Laboratory Medicine, Anatomic Pathology, and Research.
  • Laboratory Medicine is comprised of sections providing 24/7 care to CHOP patients: specifically, Chemistry, Hematology, Coagulation, Blood Bank, Microbiology, Immunology, Immunogenetics, Phlebotomy, Central Receiving, Point-of-care, and Information Systems. In addition, the highly-specialized laboratories of Virology, Metabolics, Molecular Genetics, Cancer Cytogenetics and Cytogenetics also provide state-of-the-art and unique testing to regional and national clients.
  • Anatomic Pathology consists of Surgical Pathology, Hematopathology, Neuropathology and Autopsy, with strong consultative services in gastrointestinal pediatric pathology and pediatric neuropathology.
  • Research is focused in three main areas: Cell Pathology (diseases of childhood such as diabetes, coagulation disorders, autoimmune disorders), Transplantation Immunology, and Developmental Biology (with a focus on diseases of brain development).
  • P&LM-run research cores based at the Joseph Stokes Research Institute at CHOP are: Proteomics, Pathology (including tissue microarray, laser-capture micro-dissection, immunohistochemistry, confocal microscopy), Transgenic and Knockout Mouse Facility.

Contact:

Bryan Wolf, MD, PhD, Pathologist-in-Chief
215-590-2869
wolfb@mail.med.upenn.edu

Nagin Patel, Administrative Director
pateln@email.chop.edu