Transfusion Medicine
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Apheresis
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Blood Bank
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Cellular Therapy
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Cellular Therapy
Overview
Cellular therapy activities within the Division of Transfusion Medicine comprise the collection of cells from patients in the Apheresis Unit, the processing of those cells in the Hematopoietic Stem Cell Laboratory and/or Clinical Cell and Vaccine Production Facility (CVPF), and the transfusion of the processed products back into patients.
Highlights
- A variety of cell-based therapies involving bone marrow-derived cells such as lymphocytes, dendritic cells and stem cells are currently ongoing or in development.
- In addition, non-marrow derived cells such as neural stem cells, islet cells and myoblasts can be processed in the CVPF.
- Processing techniques include: isolation/enrichment of particular cell lineages; cryopreservation and storage of cells and tissues; RNA isolation from tumor, growth and expansion of cells; and transduction (insertion) of experimental therapeutic genes into cells.
Contact
Don L. Siegel, MD, PhD
215-662-3942
siegeld@mail.med.upenn.edu
Link
www.med.upenn.edu/bmcrc/CCVPF/
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