Overview
This laboratory performs routine and specialized coagulation testing for over 35 regional laboratories and hospitals, while also accommodating requests from laboratories nationwide. This testing often includes drawing fresh specimens for platelet-related workups and meeting with physicians specializing in coagulation testing.
The Clinical Coagulation Laboratory has deep experience in performing Heparin-induced Thrombocytopenia assays, including the serotonin release assay, and has performed approximately 10,000 such tests over the past 20 years. It also has performed ELISA assays for PF4/Heparin antibodies for more than 10 years.
Highlights:
- Specialized tests to diagnose platelet disorders and immune-mediated Thrombocytopenias, as well as routine assays. Testing for Von Willebrand's disease includes standard assays for factor VIII antigen, factor VIIIC, and ristocetin co-factor, as well as assays to differentiate qualitative and quantitative disease. Assays for lupus inhibitor, and anticardiolin, b2 glycoprotein I, and prothrombin are routinely performed.
- At the forefront of testing for Heparin Antibodies, it currently performs the gold standard Serotonin Release Assay as well as the ELISA based PF4/Heparin assay.
- Drug-induced Thrombocytopenia testing and a test for Factor VII Padua can also be arranged.
Contact:
Laboratory: 7 Founders
Douglas B. Cines, MD, Director
215-662-3966
dcines@mail.med.upenn.edu
Eleanor S. Pollak, MD, Assistant Director
215-590-6117
Pollak@mail.med.upenn.edu
Barbara Konkle, MD, Director
Penn Comprehensive Hemophilia and Thrombosis Program
Presbyterian Medical Arts Building, Suite 103
1-800-789-7366
Link:
Hemophilia Program:
http://www.uphs.upenn.edu/hematol/hemophilia 
